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Measurement of fibrinogen in plasma. Detection of low fibrinogen concentrations. Detection of elevated fibrinogen concentrations (> 4g/L): In clinical situations associated with inflammation Risk factor for cardiovascular disease and thrombosis Hypofibrinogenemia, mainly associated with severe liver disease, and excessive consumption of fibrinogen (DIC, hyperfibrinolysis). Numerous variants of fibrinogen described, associated to asymptomatic cases, or to cases with bleeding and/or thrombosis.

Conventional thrombin time, highly sensitive to heparins and thrombin inhibitors.

Conventional thrombin time, highly sensitive to heparins and thrombin inhibitors.

Heparin studies.

Heparin studies.

Coagulation assays, such as the activated partial thromboplastin time (aPTT) or for the assays of factors of the intrinsic coagulation pathway.