CoaChrom®
Factor XIa Inhibitors
Description
This kit is designed for the determination of inhibitors of factor XIa (FXIa) in human plasma. Plasma is diluted in buffer containing an inactivator of α2‐macroglobulin. Excess FXIa is added and during an incubation period it complexes with plasma inhibitors. The remaining free FXIa is measured by its ability to cleave a chromogenic peptide substrate and liberate p‐nitroaniline (pNA). This can be measured photometrically, and the absorbance is inversely proportional to the plasma inhibition of FXIa.
Intended use
Determination of inhibitors of factor XIa (FXIa) in human plasma. For research use only.