CoaChrom^®
α2-Macroglobulin

Description

This kit is designed for the determination of α2‐macroglobulin (α2‐M) in human plasma. Diluted plasma is mixed with excess trypsin, and the α2‐M becomes complexed with the trypsin. The remaining, non‐complexed trypsin is inhibited with soybean trypsin inhibitor. The trypsin complexed with α2‐M is able to cleave substrates and releases pnitroaniline (pNA) from a suitable chromogenic peptide substrate. The pNA concentration may be measured photometrically and is proportional to the α2‐M concentration.

Intended use

Determination of α2‐macroglobulin (α2‐M) in human plasma. For research use only.